The problem of empty containers repositioning (ECR) is to dispatch the empty containers coupled with laden containers transportation flow between the surplus ports and the deficit ports according to the fixed schedule. Because this problem involves many parameters, variables and constraints, how to build and solve the model is always focus point. Aiming at this problem, firstly one loop itinerary of liner is divided into several stages to analyze the changes of two typical containers located in the ports and on board with the time evolving. Secondly, for attacking the difference between supply and demand empty containers in preview stage t and the ones in next stage t + 1, one dynamic region-to-region ECR model, which adopts the dynamic across-region port set to port set redistribution strategy, is proposed to reduce the various possible costs which commonly exist in existing static port-to-port ECR policy. Finally, through some deductive instances and contrast model we analyze these two models. Results show that in any case our proposed model has absolutely more advantages than the one who uses the static port-to-port ECR strategy. Moreover, the former has significant information support for making the safety stock of ports.