In this paper, the authors present practical insights in order to propose a Quality Management Framework for Digital Lean Manufacturing. The rationale behind this proposed framework is that the individual ISO 9000:2015 Quality Management pillars are rather different when it comes to their objectives and their tasks at hand when using Human capabilities and/or Digital technologies capabilities in a strategic way for (i) Quality Planning, (ii) Quality Control, (iii) Quality Assurance, and (iv) Quality Improvement in the context of the emerging paradigm of Digital Lean Manufacturing Systems.