This paper examines the nascent process of how Dynamic Instant Innovation (DII) is created by ambidexterity which is an individual’s capacity to be equally skillful with both hands. The influences of DII on new product development are introduced and analyzed through Holtzman’s paradox. This premise states that the greatest paradox that surrounds successful new product development is the need for free, unfettered creativity to complement disciplined, systematic processes [1]. Drawing from this paradox, strategies are proposed for new product development exploration and exploitation. A real case of needle-free injection product developed by the first author is presented using the DII concept.